1891 Beach Blvd., Suite 200
Jacksonville Beach, FL 32250

Phone: 904.249.3743
Fax: 904.249.2047

Clinic Hours:

Mon – Thurs: 7:30 a.m. – 5:00 p.m.
Frid: 7:30 a.m. – 12:00 p.m.

Weight Loss & Management for Women

Weight loss research shows that the average person will add one to two pounds around their abdomen each year between the ages of 35 and 55 without changing their eating or exercise habits.

Physiologically, these are the same years when progesterone levels begin to decline in women and testosterone production begins to drop in men. Midsection weight gain – those stubborn pounds stuck around your belly, butt, thighs, and hips – is just one signal of an underlying hormone level imbalance.

Even worse, fat cells produce even more estrogen, placing you in a no-win cycle of increasing estrogen dominance. If left unrecognized and untreated, those pounds around your middle can increase your risk of heart disease, diabetes, metabolic syndrome, thyroid disorders, certain types of cancer, dementia, and early mortality.

Estrogen Dominance and Belly Fat

Estrogen dominance causes weight gain around the belly, butt, thighs, and hips. Worse news: fat cells produce even more estrogen. When the body is estrogen dominant:

  • Hypothyroidism slows the body’s metabolism.
  • Abdominal tissues retain more water causing bloating to be a constant issue.
  • Unnatural insulin release results in constant hunger and food cravings for sweets.


Numerous studies in the last several decades have confirmed that physical activity has a positive effect on longevity and mortality. A lack of physical activity is associated with an increased risk of disease and disability.

But did you know that, in addition, regular physical activity helps balance your hormones? Exercise helps regulate cortisol production—making it less likely that surging levels will contribute to anxiety and an expanding waistline.

Studies in such respected medical publications as the Journal of National Cancer Institute and Cancer Epidemiol Biomarkers Preview have shown that after twelve months of regular exercise (30 minutes/five days per week), estrogen levels drop an average of 13 percent. Exercise can also cause the release of chemicals called endorphins into your bloodstream. Endorphins give you a feeling of happiness and positively affect your overall sense of well-being. Exercise is more than just “burning calories”; it is an important part of restoring healthy hormone balance.


The release of hormones by the pituitary gland (the “master gland” of the endocrine system) is significantly affected by lack of sleep. Researchers have found that after several days of partial sleep loss, early evening cortisol levels are much higher and take six times longer to decrease before habitual bedtime.

Medical evidence suggests a domino effect between estrogen dominance, lack of sleep, and the impaired production of the hormones “ghrelin” and “leptin.” These two hormones work together to regulate your appetite. Leptin is released by the fat cells in your body and sends a signal of satiety (“fullness”) to your brain, while ghrelin is secreted by the stomach and stimulates your appetite.

After only one day of sleep restriction, studies have found that ghrelin levels are markedly higher, while leptin levels are markedly suppressed. That’s why, when you are chronically tired, you also feel ravenously hungry. Your body is playing tricks on your brain!


When you have chronic lack of sleep, it also disrupts glucose and insulin metabolism, leading to a condition called “leptin resistance.” When you become leptin resistant, your brain can no longer “read” the signals of fullness from the leptin in your body. This leads you to overeat since you are unable to recognize when your body is “full.”

The significant impact of lack of sleep on your health is not as well known as other factors, like diet and exercise. However, more studies are proving that chronic sleep loss causes weight gain, increasing your risk for obesity and diabetes. There is also evidence that sleep loss weakens the immune system. A Gallup poll confirmed that 40 percent of American adults get less than seven hours of sleep!


A diet rich in high-fat meats (such as spare ribs, pork sausage, and bologna), french fries, commercial salad dressings, butter, lard or margarine, simple carbohydrates (white flour, white rice, sugar) has been found to upset hormone balance and increase levels of circulating estrogens. Instead, add some of the following foods into your diet to help support hormone balance and fight estrogen dominance:

Cruciferous Vegetables

The consumption of cruciferous vegetables is important. How estrogen is metabolized in the body is determined by an individual’s biochemical make-up, with some persons producing more 2-hydroxy derivatives (the “good” estrogens) and others producing more 16-hydroxyestrone (the “bad” estrogen).

Consuming large amounts of cruciferous vegetables such as broccoli, asparagus, cauliflower, spinach, brussel sprouts, celery, beetroot, kale, cabbage, parsley root, radish, turnip, collard and mustard greens has been shown to improve the production of “good” estrogen and foster an optimum 2/16 estrogen ratio.

Cruciferous vegetables contain a phytonutrient called Indole-3-Carbinol (I3C). I3C has been shown to act as a catalyst to pull estradiol down a benign pathway to 2-hydroxyestrone thus decreasing levels of the carcinogenic 16-alpha hydroxyestrone. This means that cruciferous vegetables can help decrease the body’s load of unhealthy estrogens and reduce an overall unhealthy condition of estrogen dominance.

A very noticeable benefit of eating more cruciferous vegetables will be decreased abdominal circumference of the waist. Another less obvious but very real bonus may be a reduced risk of developing breast, uterine, or prostate cancer.

Citrus Fruits

D-Limonene, found in the oils of citrus fruits, has been shown to promote detoxification of estrogen. Common citrus fruits include oranges, grapefruit, tangerines, lemons, limes and tangelos.

Research also found that, when administered an extract of D-Limonene, both male and female lab mice evidenced lower body weight.

Insoluble Fiber

There are two types of fiber: soluble and insoluble.

Soluble fiber dissolves in water and is degraded by bacteria in your colon. Soluble fiber forms a gel in your intestines which regulates the flow of waste material through your digestive tract. This type of fiber is found in oatmeal, oat bran, dried peas, beans, lentils, apples, pears, strawberries, and blueberries. Soluble fiber is good for you but, no matter how much of it you eat, it won’t influence your hormonal equilibrium.

Insoluble fiber, on the other hand, can directly impact your hormone balance by helping decrease estrogen overload. Insoluble fiber binds to extra estrogen in the digestive tract. This extra estrogen is later eliminated in the body through the feces.

According to the Harvard School of Public Health, sources of insoluble fiber include whole grains, whole wheat breads, barley, couscous, brown rice, whole-grain breakfast cereals, wheat bran, seeds, carrots, cucumbers, zucchini, celery, and tomatoes.


Ground or milled flaxseed, sesame seeds and flaxseed oil are part of a food group called lignans. The friendly bacteria in our intestines convert plant lignans into the “human” lignans, primarily enterolactone, that have a weak estrogen-like activity.

When there are low estrogen levels in the body these weak lignan ‘estrogens’ make up some of the insufficiency. When the body is estrogen dominant, however, the lignan ‘estrogens’ bind to the human body’s estrogen receptors thereby reducing human estrogen activity at a cellular level.

Supplements for Success

Hormone production and metabolism are impacted not only by the aging process, but also by environmental influences and lifestyle factors like diet, exercise, stress levels, and sleep habits.

The body works hard to maintain hormonal equilibrium and very often, the right supplements can help to facilitate this process. In our clinical practice, we have tested and observed the beneficial and balancing effects of scores of natural herbal supplements.

The best of these are available in our online store, with detailed descriptions of the role they play in hormone support. We recommend a select group of supplements to enhance healthy hormone balance and also promote weight loss and weight management.


Crave Control

Crave Control is a polyphenolic blend which has been shown to significantly increase metabolic function and support healthy weight by decreasing appetite biomarkers. It supports optimal weight and reduces cravings. It provides multidimensional support to maintain healthy blood pressure already in range.

Research has shown a statistically significant increase in the satiety hormone GLP-1. It also showed no increase in the hunger hormone ghrelin.

Estrogen Metabolizer – Diindolylmethane (DIM)

DIM is a phytonutrient akin to the Indole-3-Carbinol (I3C) found in cruciferous vegetables. DIM has unique hormonal benefits. It supports the activity of enzymes that improve estrogen metabolism by increasing the levels of 2-hydroxyestrone, e.g. the “good” estrogen.

When taken as part of a healthy diet, we have found that DIM helps support fat loss and healthy estrogen metabolism.

Estrodim CDG – DIM + Calcium D-Glucarate

Estrodim CDG contains DIM plus Calcium D- Glucarate a natural substance that promotes the body’s detoxification process and supports hormonal balance.

Calcium D-Glucarate has been found to lower unhealthy estrogen levels and thereby inhibit the development or progression of cancer.

The B Vitamins

The B Vitamins, such as B1, B2, B3, B5, B6, B12 and folate, do a lot within your body to support estrogen detoxification. Conversely, if your body is deficient in B vitamins, you will have higher levels of circulating estrogens.

B vitamins also impact estrogen activity for the hormone receptors at the cellular level.

Because the B vitamins work together to perform such vital tasks at the cellular level, I recommend that you take the entire B-complex, not just one or two of the vitamins.

7- Keto Dehydroepiandrosterone (DHEA)

Dehydroepiandrosterone (DHEA) is one of the hormones produced by the adrenal glands.

While many anti-aging enthusiasts are familiar with DHEA, far fewer are likely to be as aware of its metabolite, 7-Keto DHEA, which functions within the body to safely boost immune function and help reduce body fat.

Clinical studies have shown that, as 7-Keto DHEA levels go down in middle age, body weight tends to goes up. 7-Keto DHEA stimulates weight loss through a process called “thermogenesis.”

Studies have also demonstrated that 7-Keto does not accumulate in the body over time and is free of unhealthy side effects.

Berberine +

Berberine + features a blend of berberine and polyphenols. Berberine is a plant alkaloid used to support healthy blood glucose metabolism and a healthy insulin response. This blend has been shown to support healthy blood glucose levels and a healthy glycemic response to foods. It improves insulin sensitivity.

Studies have shown the polyphenols in Berberine + promote insulin satiety after a carbohydrate rich meal.

Metabolic Stim

Metabolic Stim is a natural and synergistic formula of ALA, Cinnamon Bark Extract, Chromium, Biotin and Vanadyl Sulfate It is used to maintain balanced blood sugar.

Research shows this blend helps to support the body’s glucose and lipid regulating mechanisms in order to help optimize energy expenditure.


ThermaBurn features two non-stimulating thermogenic agents. It encourages thermogenesis, where the body raises it temperature or energy output, helping you to burn off more calories in the form of heat.

Studies show thermogenesis stimulates your metabolism that enables you to readily burn calories which is the key to weight management.


ChitoSlim is made from shells of crustaceans to act as a super fiber. It creates a sensation of feeling full. It is able to absorb 6-8 times its weight in fats and oils. It then converts the fat molecules to a form the body does not absorb.

Since less fat is entering the body, the body turns to previously stored body fat for energy aiding in weight loss.

Get Help Shedding Those Extra Pounds

As women age, it can be even more difficult shedding those extra pounds. A healthy diet, exercise and the proper amount of sleep all help, but there are also environmental factors that can alter your hormone balance. The Ageless and Wellness Medical Center is here to help!

At Dr. Randolph’s Ageless & Wellness Medical Center, we offer many services and options to reach your weight loss goals. From customized prescriptions to the energizing and fat burning Lipo B12 shots to a full range of pharmaceutical-grade supplements that target specific weight loss concerns.

A professional at our Medical Center can evaluate your hormone balance and suggest appropriate dietary supplementation. If you are unable to make it to Florida, our supplements are available on our online Wellness Store.